The San Diego-based artist simply saw a cubist painting in his living room two years ago and declared, ‘I can do that'.Īctress Sophia Vergara bought one of his pieces this week and Channing Tatum, Jordan Belfort, and artist Shepard Fairey stopped by his booth at the Art Miami fair to check out his work, according to a spokesperson for Chase Contemporary.
Ten-year-old contemporary artist Andres Valencia’s gallery has already nearly sold out at Art Miami. All rights reserved.MIAMI – After a pandemic hiatus, the official Art Basel show is back in Miami with all its eccentric glory, a dizzying list of celebrity attendees and dozens of spin-off shows that are already generating a buzz, including a phenom child painter and a $4 million Banksy sale. Emerging therapies, controversies, and uncertainties in asthma management are also discussed.Ĭopyright © 2018 Elsevier Ltd. In this Seminar, we provide a clinically focused overview of asthma, including epidemiology, pathophysiology, clinical diagnosis, asthma phenotypes, severe asthma, acute exacerbations, and clinical management of disease in adults and children older than 5 years. New biological therapies for treatment of severe asthma, together with developments in biomarkers, present opportunities for phenotype-specific interventions and realisation of more personalised treatment. Asthma is classed as severe when requiring high-intensity treatment to keep it under control, or if it remains uncontrolled despite treatment. Pharmacological treatment is based on a cycle of assessment and re-evaluation of symptom control, risk factors, comorbidities, side-effects, and patient satisfaction by means of shared decisions. Anti-inflammatory and bronchodilator treatments are the mainstay of asthma therapy and are used in a stepwise approach.
The goal of asthma treatment is to achieve good asthma control-ie, to minimise symptom burden and risk of exacerbations. Asthma is a consequence of complex gene-environment interactions, with heterogeneity in clinical presentation and the type and intensity of airway inflammation and remodelling. Asthma-one of the most common chronic, non-communicable diseases in children and adults-is characterised by variable respiratory symptoms and variable airflow limitation.
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